The Dean of Medicine and hospital administrator. Dr. Lisa Cuddy (Lisa Edelstein) is in constant conflict with House over his duties at the hospital. Although she often denounces House's diagnoses and methods, even she must admit he may be the most brilliant doctor on the staff.
From her introduction to television as Lisa E on MTV's "Awake on the Wild Side" to her current role as Dr. Lisa Cuddy on HOUSE, Lisa Edelstein is no stranger to fearless roles. In the last several years, Edelstein has portrayed Rob Lowe's call-girl girlfriend on "The West Wing," the transsexual boyfriend of James LeGros on "Ally McBeal," David Conrad's lesbian sister on "Relativity" and an Orthodox Jew losing custody of her child on "Family Law." Edelstein was again tapped by David E. Kelley, this time to play James Spader's love interest on "The Practice."
Additional television credits include her series regular role on "Leap of Faith" and guest turns on the likes of "Seinfeld," "Without a Trace," "Frasier" and "ER," to name a few. Edelstein also works extensively in the realm of voiceover, most recently as "Mercy Grave" on the animated "Superman" and "Justice League" series.
In feature films, Edelstein is probably best known as Ben Stiller's aerobics-obsessed date in "Keeping the Faith," directed by Edward Norton. Additional credits include Mel Gibson's "What Women Want," "Daddy Day Care" with Eddie Murphy, "As Good As It Gets," the comedies "Say Uncle" and "Grilled" with Ray Romano and Kevin James, and the dramatic cable feature "Fathers and Sons."
After honing her craft at NYU's Tisch School of the Arts, Edelstein performed in numerous off- and off-off-Broadway productions, including the AIDS-related musical "Positive Me," which she authored, composed and performed.
Edelstein lives in Los Angeles in a century-old home with her cat and menagerie of rescue dogs. She is an avid practitioner of Ashtanga Yoga and volunteers her time by working with the Best Friend Animal Sanctuary.